Viagra 100 mg contains sildenafil, a prescription medication belonging to the phosphodiesterase type 5 (PDE5 inhibitor) class. It is used to treat erectile dysfunction (ED) in adult men.
Sildenafil works by increasing blood flow to penile tissue during sexual stimulation, helping support an erection. It does not directly increase sexual desire and does not cause an erection without sexual stimulation.
For authoritative patient information, consult MedlinePlus – Sildenafil.
Viagra 100 mg is prescribed for adult men experiencing erectile dysfunction, a condition involving difficulty achieving or maintaining an erection sufficient for sexual activity.
ED can have many causes, including cardiovascular disease, diabetes, high blood pressure, medication effects, hormonal factors, stress, and psychological conditions.
Persistent erectile difficulties should be discussed with a healthcare professional because ED may sometimes be associated with an underlying health condition.
During sexual stimulation, nitric oxide is released in penile tissue. This promotes production of cyclic guanosine monophosphate (cGMP), which relaxes smooth muscle and increases blood flow.
Sildenafil inhibits the PDE5 enzyme, helping preserve cGMP activity and supporting penile blood flow.
Sexual stimulation is required for the medication to produce an erection.
100 mg is the highest standard tablet strength of Viagra. It is not automatically the appropriate dose for every patient.
For erectile dysfunction, sildenafil is generally prescribed as an as-needed medication. A healthcare professional may select 25 mg, 50 mg, or 100 mg depending on effectiveness, tolerability, age, medical conditions, and interacting medications.
Sildenafil should normally be taken approximately 30–60 minutes before sexual activity and should not ordinarily be taken more than once in a 24-hour period.
Patients should take the dose specifically prescribed to them and should not increase the dose independently.
Sildenafil commonly begins working within approximately 30–60 minutes.
The onset can vary between individuals. Taking sildenafil with a high-fat meal may delay absorption and make the onset slower.
Sexual stimulation is still necessary for an erection to occur.
Sildenafil's effects can remain useful for several hours, but this does not mean an erection should remain continuously present.
An erection lasting more than four hours requires emergency medical attention because prolonged erections can cause permanent tissue damage.
Potential side effects of Viagra include:
Headache
Flushing
Indigestion
Nasal congestion
Dizziness
Nausea
Temporary visual changes
Side effects can vary between individuals. Severe, persistent, or unusual symptoms should be evaluated by a healthcare professional.
Sildenafil must not be taken with nitrate medications.
Examples include nitroglycerin and isosorbide medicines used for certain types of chest pain.
Combining sildenafil with nitrates can cause a potentially life-threatening reduction in blood pressure.
Patients taking nitrate medication should tell their healthcare professional before using sildenafil.
Sildenafil should not be combined with riociguat, which is used for certain forms of pulmonary hypertension.
Both medicines can lower blood pressure, and their combination can cause dangerously low blood pressure.
Sildenafil can enhance the blood-pressure-lowering effects of alpha-blockers.
People taking medications such as doxazosin or tamsulosin should tell their healthcare professional before taking sildenafil.
The clinician may recommend a lower dose or additional monitoring.
Viagra should not be combined with other PDE5 inhibitors or erectile-dysfunction treatments unless specifically directed by a healthcare professional.
This includes medications containing:
Tadalafil
Vardenafil
Avanafil
Other sildenafil products
Combining ED medications can increase the risk of low blood pressure and other adverse effects.
Sexual activity can place additional stress on the cardiovascular system.
People with significant heart disease or those who have been advised to avoid sexual activity should consult a healthcare professional before using sildenafil.
Tell your healthcare professional about:
Heart disease
Angina
Previous heart attack
Previous stroke
High or low blood pressure
Irregular heartbeat
Other cardiovascular conditions
If chest pain occurs during sexual activity, seek emergency medical attention.
Rare but serious vision problems have been reported with PDE5 inhibitors.
Seek urgent medical attention if sudden vision loss or a significant change in vision occurs.
Individuals with certain inherited retinal disorders may require additional evaluation before using sildenafil.
Rare cases of sudden hearing loss have been reported in people taking PDE5 inhibitors.
Seek prompt medical attention if sudden hearing loss, ringing in the ears, or significant hearing changes occur.
An erection lasting longer than four hours is a medical emergency.
Without prompt treatment, priapism can damage penile tissue and may lead to permanent erectile dysfunction.
Alcohol can temporarily lower blood pressure and may increase dizziness when combined with sildenafil.
Large quantities of alcohol may also make it harder to achieve or maintain an erection.
Patients should discuss alcohol use with their healthcare professional, particularly if they have cardiovascular conditions or take blood-pressure medications.
Tell your doctor or pharmacist about all prescription medications, over-the-counter medicines, vitamins, and supplements you use.
Potentially important interactions include:
Nitrates
Riociguat
Alpha-blockers
Certain blood-pressure medicines
Other PDE5 inhibitors
Certain antifungal medications
Certain antibiotics
HIV medications
Medicines that inhibit CYP3A4
Some medications can increase sildenafil concentrations and may require a lower dose.
Before taking Viagra, tell your healthcare professional if you have:
Heart disease
Blood-pressure abnormalities
Liver disease
Kidney disease
A previous heart attack or stroke
Certain eye or retinal conditions
A history of prolonged erections
Penile anatomical abnormalities
Certain blood disorders
Bleeding problems
Your healthcare professional can determine whether sildenafil is appropriate and whether a different dose should be considered.
Store Viagra according to the instructions on the medication label and pharmacy packaging.
Keep the medication securely away from children and anyone for whom it was not prescribed.
Do not share prescription medication with another person.
Unused medication should be disposed of through an appropriate medication take-back program.
Viagra 100 mg contains sildenafil, a PDE5 inhibitor prescribed to treat erectile dysfunction in adult men.
Yes. Standard Viagra tablets are available in 25 mg, 50 mg, and 100 mg strengths, with 100 mg being the highest standard tablet strength.
No. The appropriate dose varies according to individual response, medical history, age, other medications, and tolerability. A healthcare professional should determine the appropriate dose.
When prescribed for as-needed treatment of ED, sildenafil is generally taken approximately 30–60 minutes before sexual activity. It should normally not be taken more than once in 24 hours.
No. Sildenafil supports the erectile response to sexual stimulation but does not directly produce an erection or increase sexual desire.
No. Sildenafil must not be combined with nitrate medications because the combination can cause a dangerous drop in blood pressure.
Sildenafil and tadalafil should not be combined unless specifically instructed by a healthcare professional.
Seek emergency medical attention immediately. A prolonged erection can cause permanent damage to penile tissue.
No. Sildenafil improves erectile function during sexual stimulation but does not directly increase sexual desire.
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