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Cialis 20 mg contains tadalafil, a prescription medication belonging to the phosphodiesterase type 5 (PDE5) inhibitor class. It is primarily prescribed for the treatment of erectile dysfunction (ED) in adult men.
Tadalafil works by increasing blood flow to the penis during sexual stimulation, helping support an erection. It does not directly increase sexual desire and does not normally produce an erection without sexual stimulation.
For authoritative patient information, see MedlinePlus – Tadalafil.
Cialis 20 mg may be prescribed for erectile dysfunction when a healthcare professional determines that this strength is appropriate.
Erectile dysfunction can involve difficulty obtaining or maintaining an erection sufficient for sexual activity. Tadalafil improves the physiological blood-flow response involved in an erection when sexual stimulation occurs.
Tadalafil does not treat every underlying cause of erectile dysfunction, and treatment may also involve addressing cardiovascular health, diabetes, hormonal conditions, psychological factors, lifestyle factors, or other contributing conditions.
Tadalafil inhibits the PDE5 enzyme. During sexual stimulation, nitric oxide signaling increases levels of cyclic guanosine monophosphate (cGMP), which relaxes smooth muscle and increases blood flow within the penis.
PDE5 breaks down cGMP. By inhibiting PDE5, tadalafil helps maintain the signaling required for an erection.
Sexual stimulation is still required.
For as-needed treatment of erectile dysfunction, tadalafil dosing is individualized. The FDA prescribing information describes 10 mg as a usual starting dose, with the dose potentially adjusted to 5 mg or 20 mg depending on effectiveness and tolerability.
The maximum recommended frequency for as-needed tadalafil is once per day. Patients should take the medication only according to their prescription and should not increase the dose independently.
Tadalafil may be taken with or without food.
For detailed prescribing information, consult DailyMed – Tadalafil.
Tadalafil has a relatively long duration of action compared with some other PDE5 inhibitors. Its effects may remain useful for up to approximately 36 hours after an as-needed dose.
This does not mean that an erection lasts for 36 hours. An erection requires sexual stimulation, and a prolonged erection lasting more than four hours requires emergency medical attention.
Possible side effects include:
Headache
Indigestion
Back pain
Muscle aches
Flushing
Nasal congestion
Pain in the limbs
Dizziness
Side effects may vary depending on the individual and other medications being taken.
Patients should contact a healthcare professional if side effects are severe, persistent, or concerning.
Tadalafil should not be taken with nitrate medicines such as nitroglycerin or isosorbide medications.
The combination can produce a significant and potentially dangerous decrease in blood pressure.
Patients who use nitrate medication for chest pain should inform their healthcare professional before taking tadalafil.
Tadalafil should not be combined with guanylate cyclase stimulators such as riociguat because the combination may cause a substantial reduction in blood pressure.
Tadalafil can interact with alpha-blockers and may increase the risk of low blood pressure, dizziness, or fainting.
Patients should discuss all blood-pressure medications with their doctor or pharmacist.
Large amounts of alcohol can increase the likelihood of dizziness, headache, rapid heartbeat, and low blood pressure when combined with tadalafil.
People who regularly consume significant amounts of alcohol or who take blood-pressure medications should discuss alcohol use with their healthcare professional.
An erection lasting more than four hours requires immediate medical attention. A prolonged erection can damage penile tissue and potentially cause permanent erectile dysfunction.
Sudden loss or significant changes in vision require immediate medical evaluation.
Sudden hearing loss or major changes in hearing should receive prompt medical attention.
Facial or throat swelling, difficulty breathing, severe rash, or difficulty swallowing can indicate a serious allergic reaction and requires emergency care.
Sexual activity places additional demands on the cardiovascular system. People with significant cardiovascular disease should discuss sexual activity and erectile-dysfunction treatment with their healthcare professional.
A physician can determine whether tadalafil is appropriate based on cardiovascular health, other medical conditions, and current medications.
Patients should tell their doctor or pharmacist about all prescription medications, over-the-counter medicines, vitamins, and supplements they use.
Important interactions may involve:
Nitrate medications
Alpha-blockers
Certain antihypertensive medicines
Riociguat
Other PDE5 inhibitors
Other erectile-dysfunction treatments
Certain antifungal medications
Some antibiotics
Certain HIV medicines
Medicines that affect tadalafil metabolism
Tadalafil should not be combined with another PDE5 inhibitor or erectile-dysfunction medication unless specifically directed by a healthcare professional.
Tadalafil is available in several strengths and dosing approaches. A 20 mg tablet is generally associated with as-needed treatment for erectile dysfunction, while lower-strength daily regimens may be prescribed for appropriate patients.
A higher strength is not necessarily more appropriate for every patient. Healthcare professionals consider effectiveness, side effects, other medications, and underlying health conditions when selecting a dose.
Cialis 20 mg contains tadalafil, a PDE5 inhibitor prescribed primarily for erectile dysfunction.
No. Tadalafil does not directly increase sexual desire. It improves blood flow involved in achieving an erection when sexual stimulation occurs.
Tadalafil's effects may remain useful for up to approximately 36 hours after an as-needed dose in some people. This does not mean that an erection remains present for that entire period.
The appropriate dosing schedule depends on the prescription. Patients should not take 20 mg daily unless specifically instructed by a healthcare professional.
No. Combining tadalafil with nitrates can cause a potentially dangerous reduction in blood pressure.
Yes. Tadalafil can generally be taken with or without food.
Seek emergency medical attention immediately. A prolonged erection can cause permanent tissue damage.
Keep tadalafil in its original packaging and store it according to the instructions provided by the dispensing pharmacy. Keep it away from children and do not share prescription medication with another person.
This information is provided for educational purposes and does not replace professional medical advice, diagnosis, or treatment. Cialis (tadalafil) is a prescription medication and may not be appropriate for everyone.
Always follow your healthcare professional's instructions. Consult a doctor or pharmacist before starting, stopping, or changing treatment, particularly if you take nitrates, alpha-blockers, blood-pressure medicines, or other medications that may interact with tadalafil.
For additional authoritative information, consult MedlinePlus – Tadalafil, FDA – Cialis, and DailyMed – Tadalafil.
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