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Levitra 20 mg contains vardenafil, a prescription medication belonging to the phosphodiesterase type 5 (PDE5) inhibitor class. It is used to treat erectile dysfunction (ED) in adult men.
Vardenafil works by increasing blood flow to the penis during sexual stimulation, helping support an erection. It does not directly increase sexual desire and does not produce an erection without sexual stimulation.
For additional patient information, consult MedlinePlus – Vardenafil.
Levitra 20 mg is prescribed for erectile dysfunction, a condition characterized by difficulty achieving or maintaining an erection sufficient for sexual activity.
Vardenafil helps improve the erectile response by increasing blood flow to penile tissue when a person is sexually stimulated. It does not cure the underlying causes of ED or increase sexual desire.
ED can sometimes be associated with cardiovascular disease, diabetes, high blood pressure, hormonal problems, medication effects, or psychological factors. Persistent erectile difficulties should therefore be discussed with a healthcare professional.
During sexual stimulation, the body releases nitric oxide, which contributes to the production of cyclic guanosine monophosphate (cGMP). cGMP helps relax smooth muscle and increase blood flow in penile tissue.
Vardenafil inhibits the PDE5 enzyme, helping maintain cGMP activity and supporting increased blood flow during sexual stimulation.
Sexual stimulation remains necessary for the medication to produce an erection.
Vardenafil is generally taken as needed approximately 60 minutes before sexual activity. It is normally taken no more than once during a 24-hour period.
The 20 mg strength is the highest commonly available strength of standard vardenafil tablets. It should only be used when specifically prescribed by a healthcare professional.
Patients should take vardenafil exactly as directed. Do not take additional doses or increase the prescribed amount if the medication does not appear to work as expected.
A healthcare professional may prescribe a lower strength depending on age, medical conditions, other medicines, or individual response.
Levitra does not automatically produce an erection.
Sexual stimulation is necessary for vardenafil to work. The medication supports the body's natural erectile response rather than directly causing sexual arousal.
Possible side effects of vardenafil include:
Headache
Flushing
Upset stomach
Heartburn
Stuffy or runny nose
Flu-like symptoms
Dizziness
Patients should contact their healthcare professional if side effects are severe, persistent, or unusual.
Vardenafil must not be taken with nitrate medications, including nitroglycerin and isosorbide medicines.
The combination can cause a dangerous drop in blood pressure that may result in fainting, heart complications, or other serious consequences.
Anyone using nitrate medication for chest pain should tell their healthcare professional before taking vardenafil.
Vardenafil should not be taken with riociguat, because combining these medications can cause excessive blood-pressure reduction.
Products containing nitrates, sometimes referred to as "poppers," should not be combined with vardenafil because of the risk of dangerous hypotension.
Vardenafil should not be combined with other PDE5 inhibitors or other erectile-dysfunction treatments unless specifically directed by a healthcare professional.
This includes medicines containing:
Sildenafil
Tadalafil
Avanafil
Other vardenafil products
Using multiple ED medicines together can increase the risk of low blood pressure and other adverse effects.
Sexual activity can place additional stress on the cardiovascular system.
Patients with heart disease or those who have been advised to avoid sexual activity for medical reasons should discuss their cardiovascular health with a healthcare professional before using vardenafil.
Tell your healthcare professional about a history of:
Heart attack
Stroke
Angina
Abnormal blood pressure
Irregular heartbeat
Other significant cardiovascular disease
If chest pain develops during sexual activity, seek immediate medical attention.
Rare but serious vision problems have been reported in people taking PDE5 inhibitors.
Seek immediate medical attention for:
Sudden severe vision loss
Sudden changes in vision
Significant changes in color perception
Anyone experiencing sudden vision loss should stop taking vardenafil and seek urgent medical evaluation.
Sudden hearing loss or a significant decrease in hearing has also been reported rarely.
Seek prompt medical attention if sudden hearing loss occurs, particularly when accompanied by ringing in the ears or dizziness.
An erection lasting more than four hours is a medical emergency.
Prolonged erections can damage penile tissue and may lead to permanent erectile dysfunction if treatment is delayed.
Seek emergency medical attention immediately if an erection does not subside.
Patients should tell their healthcare professional about every prescription medication, over-the-counter medicine, vitamin, and supplement they use.
Important potential interactions include:
Nitrate medications
Riociguat
Alpha-blockers
Certain blood-pressure medications
Other PDE5 inhibitors
Certain antifungal medicines
Certain antibiotics
HIV medications
Medicines that affect CYP3A4 enzymes
Some combinations may require a lower dose, additional monitoring, or complete avoidance.
Alcohol can contribute to dizziness and lower blood pressure. Combining substantial amounts of alcohol with vardenafil may increase these effects.
Patients should discuss alcohol consumption with their healthcare professional, especially if they have cardiovascular disease or take blood-pressure-lowering medicines.
Vardenafil tablets can generally be taken with or without food. However, patients should follow the instructions provided with their specific prescription.
Patients should also discuss grapefruit or grapefruit juice with their healthcare professional because grapefruit can interact with vardenafil.
Before using vardenafil, tell your healthcare professional if you have:
Heart disease
High or low blood pressure
Previous heart attack or stroke
Irregular heartbeat
Liver disease
Kidney disease
A history of prolonged erections
Penile deformity
Certain blood disorders
Significant vision problems
Retinitis pigmentosa
Long QT syndrome
Your healthcare professional can determine whether vardenafil is appropriate and whether a different dose or additional monitoring is necessary.
Keep vardenafil in its original container, tightly closed, and store it at room temperature away from excessive heat and moisture.
Keep medication out of the reach of children.
Unused medication should be disposed of through an appropriate medication take-back program rather than being shared with another person.
Levitra 20 mg contains vardenafil, a PDE5 inhibitor prescribed to treat erectile dysfunction in adult men.
Vardenafil inhibits PDE5 and supports increased blood flow to penile tissue during sexual stimulation. Sexual stimulation is necessary for the medication to produce an erection.
Vardenafil is generally taken approximately 60 minutes before sexual activity when used as needed. It ordinarily should not be taken more than once in 24 hours.
For standard vardenafil tablets, 20 mg is the highest commonly available strength. The appropriate dose should be determined by a healthcare professional.
Vardenafil should not be combined with sildenafil, tadalafil, or other PDE5 inhibitors unless specifically instructed by a healthcare professional.
No. Vardenafil should not be taken with nitrate medications because the combination can cause a potentially dangerous drop in blood pressure.
No. Vardenafil improves the physical erectile response to sexual stimulation but does not directly increase sexual desire.
Seek emergency medical attention immediately. A prolonged erection can permanently damage penile tissue if not treated promptly.
This information is provided for educational purposes and does not replace professional medical advice, diagnosis, or treatment. Vardenafil is a prescription medication and may not be appropriate for everyone.
Always follow the instructions provided by your prescribing clinician and pharmacist. Do not increase the dose, take vardenafil more frequently than prescribed, or combine it with other erectile-dysfunction medicines without professional medical advice.
For additional authoritative information, consult MedlinePlus – Vardenafil and your pharmacist or prescribing healthcare professional.
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